Introduction to Chronic Inflammatory Response Syndrome (CIRS)
Abstract
Chronic inflammatory response syndrome (CIRS) is a multi-symptom, multisystem illness that is common and often missed by physicians. CIRS is a defect in antigen presentation that prevents the patient from clearing biotoxins. Some of these biotoxins are from water-damaged buildings, Lyme, cyanobacteria, Pfiesteria and ciguatera. Common complaints include fatigue, aches, cramps, sinus issues, shortness of breath, word-finding issues, memory issues and poor sleep. All physicians should know how to screen and identify CIRS. Symptom review, visual contrast sensitivity, biomarkers and history help diagnose CIRS. Transcriptomics has provided cutting-edge information on the genes that are associated with CIRS. One recent development from GENIE includes the role of actinobacteria and endotoxins in CIRS. Implementing the knowledge about CIRS universally would alleviate the suffering of millions.
Key Biomarkers
Symptom Clusters
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